2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W088846
    7-Aminonimetazepam
    7-Aminonimetazepam is the metabolite of Nimetazepam, which is found in the urine.
    7-Aminonimetazepam
  • HY-W753452
    N,N-Dimethyltryptamine N-oxide-d6
    N,N-Dimethyltryptamine N-oxide-d6 is the deuterium labeled N,N-Dimethyltryptamine N-oxide (HY-W576312). N,N-Dimethyltryptamine N-oxide is a metabolite of N,N-Dimethyltryptamine.
    N,N-Dimethyltryptamine N-oxide-d<sub>6</sub>
  • HY-W012187R
    3,5-Di-tert-butyl-4-hydroxybenzaldehyde (Standard)
    3,5-Di-tert-butyl-4-hydroxybenzaldehyde (Standard) is the analytical standard of 3,5-Di-tert-butyl-4-hydroxybenzaldehyde. This product is intended for research and analytical applications. 3,5-Di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO) is a metabolite of Butylated hydroxytoluene (HY-Y0172) .
    3,5-Di-tert-butyl-4-hydroxybenzaldehyde (Standard)
  • HY-135731AS
    4-Methylamino antipyrine-d3 hydrochloride
    4-Methylamino antipyrine-d3 (hydrochloride) is deuterium labeled 4-Methylamino antipyrine (hydrochloride). 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties.
    4-Methylamino antipyrine-d<sub>3</sub> hydrochloride
  • HY-133247
    Daclatasvir Impurity B
    Daclatasvir Impurity B is the impurity of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor.
    Daclatasvir Impurity B
  • HY-115722
    (S)-(-)-MRJF22
    (S)-(-)-MRJF22 is haloperidol metabolite II valproate ester. (S)-(-)-MRJF22 exhibits the high antimigratory effects in endothelial and tumor cells. (S)-(-)-MRJF22 is a potential multifunctional agent against uveal melanoma.
    (S)-(-)-MRJF22
  • HY-W709120
    Mono(7-carboxyheptyl) phthalate-d4
    Mono(7-carboxyheptyl) phthalate-d4 is the deuterium labeled Mono(7-carboxyheptyl) phthalate (HY-133674). Mono(7-carboxyheptyl) phthalate is a oxidative metabolite of Di-n-octyl phthalate. Di-n-octyl phthalate (DnOP) is a plasticizer used in polyvinyl chloride plastics, cellulose esters, and polystyrene resins.
    Mono(7-carboxyheptyl) phthalate-d<sub>4</sub>
  • HY-130319
    9(S)-HEPE
    9(S)-HEPE, a hydroxy fatty acid, is a metabolite of Eicosapentaenoic acid.
    9(S)-HEPE
  • HY-120556
    tetranor-12(R)-HETE
    tetranor-12(R)-HETE is a metabolite of 12(R)-HETE formed via β-oxidation.
    tetranor-12(R)-HETE
  • HY-137387
    Carvedilol Glucuronide
    Carvedilol Glucuronide is the metabolite of Carvedilol (HY-B0006). Carvedilol (BM 14190) is an antagonist for β/α-1 adrenergic receptor. Carvedilol inhibits lipid peroxidation with an IC50 of 5 μM. Carvedilol is an antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome.
    Carvedilol Glucuronide
  • HY-150092S
    (2S,3R)-8(9)-EET-d11
    (2S,3R)-8(9)-EET-d11 is deuterium-labeled (2S,3R)-8(9)-EET (HY-150092).
    (2S,3R)-8(9)-EET-d<sub>11</sub>
  • HY-136445
    Terbuthylazine-desethyl
    Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide).
    Terbuthylazine-desethyl
  • HY-N10594
    Cirsiliol 4′-glucoside
    Cirsiliol 4′-glucoside is a free radical scavenger, found from Ruellia tuberosa L. Cirsiliol 4′-glucoside shows potential anti-diabetic activity.
    Cirsiliol 4′-glucoside
  • HY-143997S
    (Rac)-Nicotine EP impurity A-d4 hydrochloride
    (Rac)-Nicotine EP impurity A-d4 (hydrochloride) is the deuterium labeled (Rac)-Nicotine EP impurity A hydrochloride.
    (Rac)-Nicotine EP impurity A-d<sub>4</sub> hydrochloride
  • HY-W011311R
    Eicosapentaenoic acid methyl ester (Standard)
    Eicosapentaenoic acid methyl ester (Standard) is the analytical standard of Eicosapentaenoic acid methyl ester. This product is intended for research and analytical applications. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis).
    Eicosapentaenoic acid methyl ester (Standard)
  • HY-100431AR
    IMR-1A (Standard)
    IMR-1A (Standard) is the analytical standard of IMR-1A. This product is intended for research and analytical applications. IMR-1A, a acid metabolite of IMR-1, is a Notch inhibitor with an IC50 of 0.5 μM. IMR-1A has a 50-fold increase in potency with respect to IMR-1. IMR-1 can metabolize in vivo to IMR-1A[1].
    IMR-1A (Standard)
  • HY-116026
    3-Hydroxycarbofuran
    3-Hydroxycarbofuran, a major metabolite of Carbofuran, is a reversible acetylcholinesterase (AChE) inhibitor.
    3-Hydroxycarbofuran
  • HY-W016099
    3-Methyl-2-quinoxalinecarboxylic acid
    3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle.
    3-Methyl-2-quinoxalinecarboxylic acid
  • HY-W700149
    N,O-Didesmethylvenlafaxine-d3
    N,O-Didesmethylvenlafaxine-d3 is the deuterium labeled N,O-Didesmethylvenlafaxine (HY-138818). N,O-Didesmethylvenlafaxine (NODVFX) is a metabolite of Venlafaxine (VFX; HY-B0196). Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor.
    N,O-Didesmethylvenlafaxine-d<sub>3</sub>
  • HY-N7781R
    (-)-(E)-Guggulsterone (Standard)
    (-)-(E)-Guggulsterone (Standard) is the analytical standard of (-)-(E)-Guggulsterone. This product is intended for research and analytical applications. (-)-(E)-Guggulsterone is the metabolite of Z-guggulsterone. Guggulsterone is an active constituent of guggulipid, an ayurvedic agent derived from Commiphora mukul. Guggulsterone has hypolipidaemic activity.
    (-)-(E)-Guggulsterone (Standard)
Cat. No. Product Name / Synonyms Application Reactivity